PHOTOREPAIR OF PYRIMIDINE DIMERS IN HUMAN SKIN IN VIVO
- 1 October 1981
- journal article
- research article
- Published by Wiley in Photochemistry and Photobiology
- Vol. 34 (4), 461-464
- https://doi.org/10.1111/j.1751-1097.1981.tb09025.x
Abstract
The exposure of human skin in vivo to UV radiation emitted from a sunlamp induces the formation of pyrimidine dimers. The number of dimers, as detected by UV-endonuclease, decreases following exposure of the UV-irradiated skin to visible wavelengths of light. Apparently, humans possess a mechanism by which pyrimidine dimers are photorepaired upon illumination of human skin in vivo with visible light.This publication has 27 references indexed in Scilit:
- Damage and repair in mammalian cells after exposure to non-ionizing radiations III. Ultraviolet and visible light irradiation of cells of placental mammals, including humans, and determinations of photorepairable damage in vitroMutation Research, 1980
- Culture conditions affect photoreactivating enzyme levels in human fibroblastsBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1976
- Photoreactivation of pyrimidine dimers in the DNA of normal and xeroderma pigmentosum cellsBiochemistry, 1976
- Low levels of photoreactivating enzyme in xeroderma pigmentosum variantsNature, 1975
- Photoreactivation of herpes simplex virus in human fibroblastsNature, 1975
- Xeroderma pigmentosum cells contain low levels of photoreactivating enzyme.Proceedings of the National Academy of Sciences, 1975
- DNA photoreactivating enzyme from placental mammals. Origin and characteristicsBiochemistry, 1974
- Photoreactivating enzyme from human leukocytesNature, 1974
- Lack of Photoreactivation in Human Cells Grownin VitroInternational Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine, 1970
- Photoreactivation: A radiation repair mechanism absent from mammalian cellsBiochemical and Biophysical Research Communications, 1966