OCULAR CONDITIONS COMMON IN INDIA AND THEIR LOCAL TREATMENT WITH SULFANILAMIDE

Abstract

Because of the finding of Rambo¹ that sulfanilamide applied locally in the eye, even when injected, did not produce any deleterious effect and because it was thought that the effective concentration and prolonged contact would be more easily obtained through use of the drug in the form of an ointment, this method was tried in the treatment of certain infective and noninfective conditions of the conjunctiva and cornea, e. g. trachoma, keratoconjunctivitis with adenitis and postoperative sepsis, and the sequelae of these conditions, such as xerosis and leukoma. The observations on trachoma will be published in another journal; the rest are presented herewith. Because of the effect of the drug in the noninfective as well as in the infective conditions, a study was undertaken for determination of it effects on the normal conjunctiva and cornea and on aseptic wounds of the cornea. The experimental findings seemed to confirm the