Effect of Large Doses of Iodide on the Peripheral Metabolism of Thyroxine in Rats
- 1 December 1967
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 81 (6), 1439-1441
- https://doi.org/10.1210/endo-81-6-1439
Abstract
The effect of large doses of iodide on the peripheral metabolism of thyroxine (T4) has been evaluated in studies conducted in rats in which the peripheral T4 pool was brought to specific activity equilibrium by daily injections of 131I-labeled T4 together with stable hormone. Doses of iodide as high as 5.0 mg daily failed to influence either the gastrointestinal or deiodinative routes of T4 metabolism.This publication has 5 references indexed in Scilit:
- Extrathyroidal Thyroxine Formation in Completely Thyroidectomized RatsEndocrinology, 1967
- Effect of a Malignant Tumor on Thyroxine Metabolism and Thyroid Function in the Rat1Endocrinology, 1966
- Biological Evidence for Extrathyroidal Thyroxine FormationEndocrinology, 1966
- Effect of Catalase Inhibitors on the Deiodination of ThyroxineEndocrinology, 1964
- GROWTH RESPONSE OF THYROIDECTOMIZED RATS TO HIGH LEVELS OF IODIDE1Endocrinology, 1960