THYMUS-DEPENDENT LYMPHOCYTES OF DENGUE VIRUS-INFECTED MICE SPLEENS MEDIATE SUPPRESSION THROUGH PROSTAGLANDIN
- 1 January 1981
- journal article
- research article
- Vol. 42 (1), 1-6
Abstract
Apparently transfer of spleen cells obtained from dengue type 2 virus (DV)-primed mice suppressed DV antigen-specific antibody secretion as detected by Jerne plaque-forming cell technique. The suppression was produced by non-glass-adherent cells, macrophage-depleted (by carbonyl Fe) cells and by splenic T lymphocytes, but not by the glass-adherent cells and B lymphocytes. The activity of these cells is dependent upon prostaglandin [PG] production as shown by abrogation of their suppressor activity by pre-treatment of cells by indomethacin or aspirin, which are known to block Pg synthesis.This publication has 27 references indexed in Scilit:
- Suppression of secondary plaque-forming cell responses by rat splenic adherent cells: Evidence for dependence on prostaglandin productionCellular Immunology, 1979
- Biochemical Study of Certain Enzymes and Metabolites of the Carbohydrate Metabolism in the Skeletal Muscle of the Dengue Virus-Infected MiceJournal of General Virology, 1978
- Prostaglandin E production by human blood monocytes and mouse peritoneal macrophages.The Journal of Experimental Medicine, 1978
- Suppression of human T-cell mitogenesis by prostaglandin. Existence of a prostaglandin-producing suppressor cell.The Journal of Experimental Medicine, 1977
- Contact-mediated suppression of mitogen-induced responsiveness by spleen cells in reticuloendotheliosis virus-induced tumorigenesisCellular Immunology, 1977
- The role of prostaglandins in the control of the primary 19S immune response to sRBCCellular Immunology, 1977
- B-cell suppression of delayed hypersensitivity reactionsNature, 1974
- A rapid method for the isolation of functional thymus‐derived murine lymphocytesEuropean Journal of Immunology, 1973
- BIOLOGICAL EXPRESSIONS OF LYMPHOCYTE ACTIVATIONThe Journal of Experimental Medicine, 1973
- Plaque Formation in Agar by Single Antibody-Producing CellsScience, 1963