Radiation-Induced Squamous-Cell Metaplasia and Hyperplasia of the Normal Mucous Glands of the Oral Cavity

Abstract

In the course of radiation therapy for malignant tumors of the oral cavity, squamous metaplasia of the glandular epithelium of the normal mucous membrane of the oral cavity was observed in a series of 64 cases. This represents another instance in which prolif erative changes have been induced in normal tissues by ionizing radiation.