Post-Irradiation Time and Dose-Response Studies on the Incorporation of P 32 into DNA of Mouse Tissues

Abstract
The short term incorporation of P32 into deoxyribonucleic acid (DNA) of normal mouse tissues and 2 transplanted tumors was measured at varying times after 300, 800 and 2500 r of total body X-irradiation. It was found that each tissue has a characteristic pattern of depression and recovery. For most tissues the incorporation decreases gradually, reaching a minimum value many hours after irradiation. It is suggested that cell death may be a major cause of the observed decrease of P32 incorporation.