Useful reactions of nucleophiles with some methylsulphonyl derivatives of nitrogen heterocycles

Abstract

Methods are described for the preparation of hydroxy-, mercapto-, cyano-, amino-, methylamino-, n-propylamino-, and hydrazino-derivatives of pyridine, pyrazine, pyridazine, quinoline, isoquinoline, quinoxaline, cinnoline, and phthalazine by reaction of the corresponding methylsulphonyl compound with the appropriate nucleophile.