A COMPARISON OF THE INFLUENCE OF SOME CRYSTALLINE HORMONES OF THE ADRENAL CORTEX ON THE DEPOSITION OF GLYCOGEN IN THE LIVER

Abstract
The authors studied the influence of 5 crystalline steroids of the adrenal cortex, desoxycorticosterone acetate (D C A) and an extract of the adrenal cortex on the deposition of glycogen in the liver of the fasting rat. D C A which lacks an atom of oxygen at C11, and compounds (17-hydroxy-ll-dehydro-3,4,5-tetrahydro(3[beta]hydroxy) corticosterone and ll-dehydro-3,4,5-tetrahydro(3[beta]hydroxy) corticosterone) which do not have an unsaturated ketone group in Ring A were without effect. Less than a 1-fold difference was found between compounds 11-dehydrocor-ticosterone, corticosterone, and 17-hydroxy-11-dehydrocor-ticosterone.