GABA involvement in memory consolidation: Evidence from posttrial amino-oxyacetic acid
- 1 January 1978
- journal article
- research article
- Published by Springer Nature in Psychopharmacology
- Vol. 56 (2), 191-193
- https://doi.org/10.1007/bf00431848
Abstract
In order to assess the possible effects of central GABA activation on the consolidation of shock avoidance, the GABA-T inhibitor amino-oxyacetic acid (AOAA) was administered posttrial to adult male rats. Learning was assessed over nine widely spaced sessions of 20 trials each. AOAA-treated animals showed learning within sessions and a lack of consolidation across sessions. Controls, on the other hand, showed learning both within and across sessions. This evidence agrees with previous reports suggesting GABA involvement in memory processes.Keywords
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