Uptake and metabolism of β-phenethylamine and tyramine in mouse brain and heart slices
- 12 April 1971
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 23 (4), 276-279
- https://doi.org/10.1111/j.2042-7158.1971.tb08657.x
Abstract
Tritium labelled β-phenethylamine and tyramine were incubated with slices of mouse brain and heart. Cocaine (3 × 10−5M) caused a reduction of 30% in the uptake of tyramine as well as in the formation of its metabolite 4-hydroxyphenylacetic acid. Cocaine had no effect on either the uptake of phenethylamine nor its deamination to phenylacetic acid.Keywords
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