Abnormal lactic dehydrogenase isoenzyme patterns in ulcerative colitis with precancerous change
Open Access
- 1 January 1971
- Vol. 12 (1), 16-19
- https://doi.org/10.1136/gut.12.1.16
Abstract
The isoenzyme pattern of lactic dehydrogenase was measured in rectal biopsies from six patients with ulcerative colitis in whom precancerous histological changes had been independently recognized. There was a highly significant increase in the ratio of isoenzymes IV + V to I + II. This suggests that lactic dehydrogenase isoenzyme measurement may prove a valuable addition to histology in the recognition of precancer in ulcerative colitis.Keywords
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