Effect of Insulin upon Resting Electrical Potential of Adipose Tissue.

Abstract

Significant increase of cell membrane resting electrical potential (REP) of adipose tissue obtained from young rats occurred in response to 1-1,000 micro-units/ ml of insulin. Decrease of adipose tissue resting potentials occurred following replacement of insulin by control buffer. Resting electrical potentials of adipose tissue from older rats, weighing 330-405 g, showed no such increase in response to 1,000 micro-units/ml of insulin. Presence or absence of glucose in the buffer medium appeared to have no effect upon the response of cell membrane REP.