ANALYSIS OF LEUKOCYTIC EXTRACTS FROM GUINEA PIGS HYPER-SENSITIVE TO TUBERCULIN AND 2,4-DINITROCHLOROBENZENE

Abstract

Electrophoretic and passive transfer studies were done on extracts of peritoneal exudative leukocytes from tuberculin-sensitive, 2,4-dinitrochlorobenzene-sensitive, and normal donor guinea pigs. A new electrophoretic component resembling an [alpha]-1-globulin was found in high concentration in extracts of cells from sensitive donors. This was not present in normal cells. Positive passive transfer reactions were obtained with aliquot portions of more than 70% of extracts from sensitive donor groups.