Estrogen Carcinogenesis in Breast Cancer
Top Cited Papers
- 19 January 2006
- journal article
- review article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 354 (3), 270-282
- https://doi.org/10.1056/nejmra050776
Abstract
Estrogen exposure is a major determinant of the risk of breast cancer. This article reviews how genotoxic, mutagenic metabolites of estrogen and stimulation of tissue growth by the hormone participate in the pathogenesis of breast cancer.Keywords
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