Effervescent Mixtures as Adjuvants to the Rapid Absorption of Ingested Drugs

Abstract

ALTHOUGH there are many and obvious advantages to the oral administration of drugs, there are certain equally obvious disadvantages. Of these the most prominent are the uncertain and variable rate of absorption and gastric irritation. It is probable that when irritation occurs, its intensity varies with the duration of the contact of the drug with the gastric mucosa, and that it is least when emptying of the stomach is rapid. Since few drugs are absorbed directly from the stomach, the rate of emptying affects the speed of therapeutic response, and for drugs whose action depends on concentration developed in the . . .