Cytopathogenic Mycoplasmas Associated with Two Human Tumors II. Morphological Aspects
- 1 August 1965
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 90 (2), 511-+
- https://doi.org/10.1128/jb.90.2.511-516.1965
Abstract
Cytopathic effects (CPE) produced in HeLa cell cultures by 2 strains of mycoplasmas (F-11 and F-12) were studied by light and electron microscopy. CPE, which was marked by cytoplasmic vacuolization, did not appear to depend on intracellular mycoplasma infection. The cytopathogenic mycoplasmas appeared to be similar, both morphologically and in their intra- and extracellular distribution to noncyto-pathogenic mycoplasmas previously studied by others. The probability that the CEP is related to depletion of essential nutrients is discussed, and the fine structure of the mycoplasmas is described.Keywords
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