Campylobacter pylori isolated from the stomach of the monkey, Macaca nemestrina
- 1 September 1988
- journal article
- research article
- Published by American Society for Microbiology in Journal of Clinical Microbiology
- Vol. 26 (9), 1725-1728
- https://doi.org/10.1128/jcm.26.9.1725-1728.1988
Abstract
Campylobacter pylori was isolated from the gastric mucosa in 6 of 24 pigtailed macaques (Macaca nemestrina) examined by gastric biopsy and culture; 3 isolates were recovered during gastroendoscopy, and 3 were recovered at necropsy. The isolates were morphologically and biochemically similar to the human type strain NCTC 11638, differing only in colony diameter, pigmentation, and rate of growth. Identity of the isolates was confirmed by whole-genomic DNA-DNA hybridization with the type strain. Colonization of the monkey stomachs was associated with hypochorhydria and histologic features resembling type B chronic gastritis in humans. Host animals exhibited no morbid clinical effects of colonization, although endoscopy revealed inflammation, erythema, and friable tissue in some animals. The discovery of C. pylori occurring spontaneously in M. nemestrina extends the known range of the hosts of the organism and offers the possibility of a natural or experimental model of the infection in monkeys.This publication has 13 references indexed in Scilit:
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