Toxicity of Hydroxamic Acid Analogues; Prophylactic and Therapeutic Efficacy Against Nerve Gas Poisoning in Mice.
- 1 August 1956
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 92 (4), 660-662
- https://doi.org/10.3181/00379727-92-22575
Abstract
A series of analogues of hydroxamic acid were tested for toxicity and for therapeutic efficacy against Sarin in mice. Some showed protection against 1 and 2 LD50''s of Sarin. Toxicity and protective efficacy were not correlative. Effective doses were quite large.Keywords
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