Since 1922, when Sicard and Forestier (21) first described the technic of myelography with Lipiodol, the search for an ideal contrast medium has continued. Such a contrast medium should be soluble, nontoxic, nonirritating, and hyperbaric and should provide good roentgenographic contrast. Currently, in the United States, insoluble iophendylate (Pantopaque) is widely used, whereas in Scandinavia water-soluble sodium iodomethanesulfonate (abrodil, Skiodan, Kontrast U) is popular. Arachnoiditis and other adverse effects of oil-based insoluble media, such as iophendylate, are well known (2, 3, 8, 10, 11, 13–15, 18, 23–26). The irritating properties of monoiodomethane (6, 7, 12, 22) have necessitated administration of a spinal anesthetic before performance of myelography (9). In 1964, Campbell and his associates (1) reported use of meglumine iothalamate (Conray) for ventriculography and myelography. Their studies demonstrated the low toxicity of this substance. They obtained roentgenograms of good diagnostic qu...