A method of sterilizing and preserving fresh allograft heart valves
Open Access
- 1 July 1972
- Vol. 27 (4), 398-400
- https://doi.org/10.1136/thx.27.4.398
Abstract
The present study was undertaken to find an antibiotic mixture which would rapidly and completely sterilize a heavily contaminated allograft heart valve without reducing its viability. Two different antibiotic combinations were used; formula A was used for 66 valves and formula B for 60 valves. Viability of the valves was assessed by autoradiography and tissue culture, and was found to be similar in both formulae. Formula B proved more effective; all valves were sterile after 24 hours' exposure to the antibiotics and remained so thereafter. The period of viability was greatly extended when a nutrient medium was used to store the valves.Keywords
This publication has 9 references indexed in Scilit:
- Viability of fresh aortic valve homografts: a quantitative assessmentThorax, 1972
- Use of Aortic Valve Homografts for Aortic Valve ReplacementCirculation, 1971
- Aortic homograft valve replacement. A long-term follow-up of an initial series of 101 patients.1969
- A Review of Aortic Valve Homografts over a Six and One-half Year PeriodAnnals of Surgery, 1969
- Morphology of fresh heart valve homografts.1969
- Replacement of Diseased Aortic Valves with HomograftsAnnals of Surgery, 1969
- Homograft replacement of the aortic valve: A clinical and pathologic studyThe American Journal of Cardiology, 1968
- The pathology of human aortic valve homograftsThorax, 1967
- Pathology of the human aortic valve homograft.Heart, 1966