PHOTOSENSITIZATION WITH DERIVATIVES OF CHLOROPHYLL
- 1 February 1989
- journal article
- research article
- Published by Wiley in Photochemistry and Photobiology
- Vol. 49 (2), 157-160
- https://doi.org/10.1111/j.1751-1097.1989.tb04090.x
Abstract
The properties of several chlorophyll derivatives were examined: the methyl esters of pheophorbide A, pheophorbide B and pheophytin. In spite of structural differences, all products were equally effective sensitizers in vitro and were localized equally well by murine tumors in vivo after 1 h. But only the pheophytins persisted at neoplastic loci for 24 h. There was no evidence of hydrolysis of the methyl esters, but the phytyl ester linkage was labile in vivo.This publication has 11 references indexed in Scilit:
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