Effects of Intravenous Administration of Fibrinolysin (Plasmin) in Man
- 1 July 1959
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation
- Vol. 20 (1), 42-55
- https://doi.org/10.1161/01.cir.20.1.42
Abstract
The potentiality of dissolving clots has aroused great interest in fibrinolysin (plasmin) as a therapeutic agent in thromboembolism. In this paper the effects of intravenous administration of purified fibrinolysin in man are reported, with special emphasis upon systemic toxicity and alterations in clotting factors and fibrinolytic activity. This information is necessary for the evaluation of this agent for clinical purposes.Keywords
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