Studies in General Biology of Sperm: Experimental Production of Spermatic Granuloma

Abstract

Since, in man, the interstitial tissues respond to the extravasation of sperm with a granu-lomatous reaction , it was deemed advisable to determine whether a similar lesion can be produced experimentally in animals. Study on 30 adult albino rats revealed that, when the vasa deferentia were severed and the open cut ends implanted in either the scrotal wall or the abdominal cavity and retro-peritoneum, spermatic granuloma developed.