Differential Diagnosis of Solitary Pulmonary Nodules with Positron Emission Tomography Using [11C]L-Methionine
- 1 September 1988
- journal article
- research article
- Published by Wolters Kluwer Health in Journal of Computer Assisted Tomography
- Vol. 12 (5), 794-796
- https://doi.org/10.1097/00004728-198809010-00015
Abstract
Two patient with soliatray pulmonary nodules, 1.5-2.0 cm in diameter, were studied by positron emission tomography using [11C-Methyl]L-methionine (11C-Met). Case 1 showed high accumulation of 11C-Met in the tumor, and a tumor/muscle ratio of 6.0 suggesting malignancy. Tissue obtained by biopsy revealed a squamous cell carcinoma. Case 2 showed nonspecific isotope accumulation in the tumor, and a tumor/muscle ratio of 1.2 suggesting a benign lesion. Lung biopsy demonstrated granuloma. Positron emission tomography with 11C-Met seems to be useful for the differential diagnosis of solitary lung nodules.Keywords
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