The Sensitivity of Measles Virus Haemolysin to Acetone and the Preparation of Mono-specific Human Anti-Haemolysin by Absorption

Abstract

The hemolysin of measles virus, either in the virion or in infected cells [African green monkey kidney], is functionally and antigenically sensitive to acetone. Absorption of human sera with acetone-treated, measles virus-infected cells removes antibodies to all measles virus structural antigens except hemolysin. The antibody titers of absorbed sera give good correlation in HLI [hemolysin-inhibiting antibodies], neutralization and fluorescent antibody staining on unfixed infected cells.