Relationship of the Effects of Adrenal Cortical Secretion on Lymphoid Tissue and on Antibody Titer.

Abstract

Summary Agglutinin titers to sheep erythrocytes are enhanced as a result of adrenal cortical extract injection. Titers were increased within 6 hours after a single injection of adrenal cortical extract into hyper-immunized rabbits. Increased titers produced by a single injection of adrenal cortical hormone return in 24 hours almost to levels existing before hormone administration. Continued hormone injection maintained elevated titers for 2 weeks.