Isolation and characterization of the mouse corticotropin‐β‐lipotropin precursor gene and a related pseudogene

Abstract
Two mouse genomic DNA sequences homologous with human corticotropin-β-lipotropin precursor gene sequences have been cloned. One of them represents the functional corticotropin-β-lipotropin precursor gene, which exhibits a structural organization similar to those of its bovine and human counterparts. The other represents a pseudogene that corresponds to the functional mouse gene sequence encoding the carboxy-terminal 143 amino acid residues (including corticotropin and β-lipotropin) and the 3′-untranslated region