l -α-Tocopheryl Acetate: Biological Activity

Abstract

L-α-Tocopheryl acetate has 42 percent of the activity of d-α-tocopheryl acetate when compared in the rat hemolysis test. Based on this activity a potency ratio of 1.4 : 1.0 for d-α-tocopheryl acetate compared to dl-α-tocopheryl acetate was established; this confirms the currently accepted biological ratio. Preparations of dl-α-tocopheryl acetate from phytol and from isophytol were equally active in the rat hemolysis test.