Pairwise Use of Complexity-Generating Reactions in Diversity-Oriented Organic Synthesis
- 11 February 2000
- journal article
- letter
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 2 (5), 709-712
- https://doi.org/10.1021/ol005574n
Abstract
Two pairs of complexity-generating reactions with an essential product−substrate relationship along a synthetic pathway are demonstrated. This pathway illustrates a key element in a planning algorithm for diversity-oriented synthesis. This element facilitates the efficient synthesis of structurally complex compounds, and it can be integrated with ones that provide structurally diverse compounds.Keywords
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