Variation of the α2-Macroglobulin Homologue with Age in some Mammals
- 1 January 1968
- journal article
- research article
- Published by Taylor & Francis in Scandinavian Journal of Clinical and Laboratory Investigation
- Vol. 21 (2), 177-181
- https://doi.org/10.3109/00365516809084280
Abstract
The α2-macroglobulin concentration in rat serum and dog serum was determined by an enzymatic method as well as by an immunochemical method. The results obtained showed a close correlation, indicating that the enzymatic method can be used for determination of the α2-macroglobulin homologue in sera from various mammalian species. The α1-macroglobulin in the rat is very probably an α2-macroglobulin despite its electrophoretic mobility. The concentration of α2-macroglobulin in serum from the young rat and ox was significantly lower than in serum from the adult animal. In the dog the serum concentration of α2-macroglobulin was slightly higher in young animals than in adult ones. None of the species studied showed the remarkable variation with age seen in man.Keywords
This publication has 13 references indexed in Scilit:
- Composition et structure de L'α2-Macroglobuline isolée du serum de porcBiochimica et Biophysica Acta (BBA) - Protein Structure, 1967
- Serum α2-macroglobulin concentration and its variation with age and sexClinica Chimica Acta; International Journal of Clinical Chemistry, 1967
- Determination of α2-macroglobulin as trypsin-protein esteraseClinica Chimica Acta; International Journal of Clinical Chemistry, 1966
- Separation of two trypsin-binding α2-globulins of human serumClinica Chimica Acta; International Journal of Clinical Chemistry, 1966
- Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodiesAnalytical Biochemistry, 1966
- Étude biochimique de l'α1-macroglobuline du sérum de lapin: I. Préparation et propriétés physico-chimiquesBiochimica et Biophysica Acta (BBA) - General Subjects, 1965
- Antigen-antibody crossed electrophoresisAnalytical Biochemistry, 1965
- Macroglobulin from Human Plasma Which Forms an Enzymatically Active Compound with TrypsinScience, 1964
- Studies on α2-macroglobulin I. A method for the isolation of rabbit α2-macroglobulinBiochimica et Biophysica Acta, 1963
- PROTEIN BINDING OF PANCREATIC PROTEOLYTIC ENZYMES*JCI Insight, 1962