Radioimmunoassay for Human Antithyroglobulin Antibodies of Different Immunoglobulin Classes

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Abstract
A simple, accurate, co-precipitation radioimmunoassay for the detection of human antithyroglobulin antibodies is described. This semiautomated technique allows the determination of the 3 classes of antibodies; it compares favorably with the tanned red cell hemagglutination test. Its clinical relevance is illustrated in the investigation of various thyroid diseases.