THE PULMONARY RETENTION OF AEROSOLS: A QUANTITATIVE METHOD OF MEASUREMENT USING SODIUM PARA-AMINO HIPPURATE
Open Access
- 1 September 1950
- journal article
- research article
- Published by American Society for Clinical Investigation in Journal of Clinical Investigation
- Vol. 29 (9), 1177-1181
- https://doi.org/10.1172/jci102355
Abstract
The use of this substance permits detn. of the amt. of aerosol retained by: (1) the difference between the amt. inspired and that expired and trapped in the mouth; and (2) by the amt. which is absorbed and appears in the urine. The first requires a cumbersome apparatus; the second, collection of urine over a period of 6-12 hrs. The methods check each other well, and in either case could readily be modified for study of the pulmonary retention of other substances given as aerosols by incorporating Na p-aminohippurate in the soln. to be nebulized.This publication has 2 references indexed in Scilit:
- OBSERVATIONS ON THE CLEARANCE METHOD OF DETERMINING RENAL PLASMA FLOW WITH DIODRAST, PARAAMINOHIPPURIC ACID (PAH) AND PARA - ACETYLAMINOHIPPURIC ACID (PACA)1949
- THE RENAL CLEARANCES OF SUBSTITUTED HIPPURIC ACID DERIVATIVES AND OTHER AROMATIC ACIDS IN DOG AND MAN 1Journal of Clinical Investigation, 1945