ACTION OF THYROXIN ON ESTROGEN-INDUCED CHANGES IN BLOOD CHEMISTRY AND ENDOSTEAL BONE

Abstract

The ability of thyroxin to modify a number of the effects of estradiol benzoate was tested in pigeons. The 2 hormones were injected simultaneously and in equal quantities by wt. Thyroxin did not measurably inhibit the action of estrogen on the formation of endosteal bone. It prevented the marked increase of plasma neutral fat which follows the use of estrogen alone. Confirming results obtained on immature fowl by Fleisch-mann and Fried, thyroxin was observed to inhibit estrogen-induced increases in plasma Ca, inorganic P, protein P and lipid P; and it did not inhibit the ability of estrogen to promote growth of the oviduct.