Abstract
The locus of the effect of anesthesia upon the consolidation process was investigated by using Leao''s spreading depression (SD) to produce a transient decortication and a passive avoidance response, established in 1 trial. Rats given SD within 10 min. after the trial showed some deficit in retention of the avoidance response. Ether anesthesia and SD appear to have similar effects upon consolidation in this situation.

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