Inhibition of human DNA topoisomerase II by hydroquinone and p-benzoquinone, reactive metabolites of benzene.
Open Access
- 1 December 1996
- journal article
- Published by Environmental Health Perspectives in Environmental Health Perspectives
- Vol. 104 (suppl 6), 1265-1269
- https://doi.org/10.1289/ehp.961041265
Abstract
Chronic exposure of humans to benzene (BZ) causes acute myeloid leukemia (AML). Both BZ and therapy-related secondary AML are characterized by chromosomal translocations that may occur by inappropriate recombinational events. DNA topoisomerase II (topo ...Keywords
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