Addiction Liability of Albino Rats: Breeding for Quantitative Differences in Morphine Drinking
- 4 August 1967
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 157 (3788), 561-563
- https://doi.org/10.1126/science.157.3788.561
Abstract
Selective breeding produced two strains of rats that differ in their susceptibility to morphine addiction. Inbreeding the more susceptible rats in an unselected population produced susceptible offspring; inbreeding resistant rats produced resistant offspring. Further selection and inbreeding increased the strain difference in the F2 and F3 generations. The F3 generation also differed in their susceptibility to alcohol addiction.This publication has 6 references indexed in Scilit:
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- CLINICAL STUDIES OF DRUG ADDICTIONArchives of Internal Medicine, 1942