Novel inhibitors of influenza sialidases related to GG167 structure-activity, crystallographic and Molecular dynamics studies with 4H-pyran-2-carboxylic acid 6-carboxamides
- 1 December 1996
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 6 (24), 2931-2936
- https://doi.org/10.1016/s0960-894x(96)00542-2
Abstract
No abstract availableKeywords
This publication has 6 references indexed in Scilit:
- Novel inhibitors of influenza sialidase related to GG167 Synthesis of 4-amino and guanidino-4H-pyran-2-carboxylic acid-6-propylamides; selective inhibitors of influenza a virus sialidaseBioorganic & Medicinal Chemistry Letters, 1996
- Safety and efficacy of the neuraminidase inhibitor GG167 in experimental human influenzaPublished by American Medical Association (AMA) ,1996
- Review: Anti-infectives Recent developments in the antiviral therapy of influenzaExpert Opinion on Therapeutic Patents, 1995
- Three‐dimensional structure of the complex of 4‐guanidino‐Neu5Ac2en and influenza virus neuraminidaseProtein Science, 1995
- Synthesis of 6-, 7- and 8-carbon sugar analogues of potent anti-influenza 2,3-didehydro-2,3-dideoxy-N-acetylneuraminic acid derivativesJournal of the Chemical Society, Perkin Transactions 1, 1995
- 4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid is a highly effective inhibitor both of the sialidase (neuraminidase) and of growth of a wide range of influenza A and B viruses in vitroAntimicrobial Agents and Chemotherapy, 1993