Atrial Pacing and Exercise in the Evaluation of Patients with Angina Pectoris
- 1 March 1971
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation
- Vol. 43 (3), 407-419
- https://doi.org/10.1161/01.cir.43.3.407
Abstract
The anginal threshold was determined by atrial pacing in 23 patients with coronary artery disease. Twelve of the 23 subjects also performed supine exercise at progressive workloads until the onset of angina. Atrial pacing produced a fall in left ventricular stroke work index and left ventricular end-diastolic pressure (LVEDP); cardiac output increased, and, with the onset of angina, left ventricular dysfunction was sometimes evidenced, either by an increase in LVEDP or by an abnormal LVEDP in the postpacing period. In contrast, exercise consistently produced left ventricular dysfunction. The tension-time index at the onset of angina was similar whether the pain was induced by pacing or exercise. The atrial rate that induced angina bore little relationship to either the clinical or anatomic severity (outlined by coronary arteriography) of coronary artery disease. The exercise workload that produced angina correlated inversely with the quantitated coronary disease. Although atrial pacing is a convenient tool for the study of ischemic ventricular dysfunction, exercise testing provides a more reliable index of functional and anatomic severity of coronary artery disease.Keywords
This publication has 11 references indexed in Scilit:
- The importance of design of exercise protocol in the evaluation of patients with angina pectorisThe American Journal of Cardiology, 1970
- Myocardial blood flow and exercise electrocardiogram in cinearteriographically demonstrated coronary artery diseaseThe American Journal of Cardiology, 1970
- Postexercise Electrocardiography in Patients with Arteriographically Documented Coronary Artery DiseaseAnnals of Internal Medicine, 1969
- Clinical Use of Atrial Pacing Test in Angina PectorisBMJ, 1968
- Measurement of the Angina Threshold Using Atrial Pacing: A New Technique for the Study of Angina PectorisCardiovascular Research, 1967
- Effect of tachycardia on cardiac output during normal and increased venous returnAmerican Journal of Physiology-Legacy Content, 1966
- A hemodynamic study of acute coronary insufficiency precipitated by exerciseThe American Journal of Cardiology, 1966
- Relationships between left ventricular ejection time, stroke volume, and heart rate in normal individuals and patients with cardiovascular diseaseAmerican Heart Journal, 1961
- Variable Resistance Bicycle Ergometer for Performance of Recumbent ExerciseReview of Scientific Instruments, 1957