Replicative Intermediate of an Arbovirus
- 1 June 1968
- journal article
- research article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 2 (6), 547-+
- https://doi.org/10.1128/jvi.2.6.547-552.1968
Abstract
One hr. after infection of chick fibro-blasts with Semliki Forest virus (SFV), a viral RNA structure is present which has many of the properties described for the replicative intermediate of several RNA bacteriophages. These properties include a polydisperse nature on sucrose density gradient analysis, RNase resistance, a variation in sedimentation pattern associated with changes in salt concentration, and recovery of infectious viral RNA upon denaturation. Most of the replicative intermediate present in SFV infection appears to be membrane-associated.This publication has 16 references indexed in Scilit:
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