Effects of Fructose on Hypoglucosemia in Infants of Diabetic Mothers

Abstract
GESTATIONAL diabetes (termed "pre-diabetes" by some investigators) offers a unique opportunity to investigate the influence of an altered maternal environment on the carbohydrate metabolism of the newborn infant. Previous attention has been called to infants of insulin-dependent mothers.1 2 3 4 The present observations indicate that hypoglucosemia†† is a common phenomenon in infants of mothers with gestational diabetes as well and that it is related to the degree of maternal glucose intolerance. The influence of fructose on the infant's metabolism of glucose was also evaluated.MethodsFrom July, 1963, to August, 1965, 60 normal infants and 56 infants of diabetic mothers from greater . . .