Sarcoid neuropathy
- 1 June 1991
- journal article
- Published by Springer Nature in Zeitschrift für Neurologie
- Vol. 238 (3), 177-180
- https://doi.org/10.1007/bf00319686
Abstract
In a case of subacute sensory and motor polyneuropathy associated with sarcoidosis, multiple epineurial and endoneurial granulomas were demonstrated in a sural nerve. Neighbouring nerve fibres were displaced by the granulomas and some were undergoing axonal degeneration. Ultrastructural and teased fibre studies showed axonal atrophy and degeneration with secondary demyelination. Histochemical studies indicated the presence of HLA-DR antigen on epithelioid cells in the granulomas. A non-specific inflammatory process in the nerve does not cause significant primary demyelination.Keywords
This publication has 11 references indexed in Scilit:
- Peripheral nerve pathological findings in familial amyloid polyneuropathy: A correlative study of proximal sciatic nerve and sural nerve lesionsAnnals of Neurology, 1989
- The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infectionCell, 1989
- Tumor Necrosis Factor Mediates Myelin Damage in Organotypic Cultures of Nervous TissueaAnnals of the New York Academy of Sciences, 1988
- Teased fibre studies in leprous neuropathyJournal of the Neurological Sciences, 1987
- Sarcoidosis of the Peripheral Nerve: Clinical, Electrophysiological and Histological Study of Two CasesEuropean Neurology, 1984
- Sarcoidosis of the peripheral nerve: A histological and ultrastructural study of two casesActa Neuropathologica, 1982
- Symmetric sarcoid polyneuropathyNeurology, 1981
- Neurologische Manifestationen der SarkoidoseZeitschrift für Neurologie, 1967
- Neurological manifestations of sarcoidosisNeurology, 1965
- THREE TYPES OF NERVE INJURYBrain, 1943