The feeding and breeding of laboratory animals: VII. Methods of testing the adequacy of diets for breeding mice

Abstract

1. The application of factorial design to. the testing of diets for breeding mice is described.2. The use of a system of monogamous making, by which the females have a continuous series of pregnancies with concurrent gestation and lactation, is advocated for such tests.3. Present indications are that a high wheat content or a high yeast content is desirable in the diet of breeding mice.4. A diet containing a considerable proportion of full-cream milk was very effective for breeding mice, but it is not yet certain that this constituent is necessary.