Dynamic Clinical Studies With Radioisotopes and the Scintillation Camera

Abstract
The scintillation camera has been used for dynamic studies of renal function with sodium iodohippurate I 131 (Hippuran). This approach permits constant visual monitoring of the passage of iodohippurate I 131 through the parenchyma and pelvis of the kidney concomitant with the inscription of the renogram curve. It thus permits more definitive interpretation of the renogram since it allows direct, rather than intuitive, correlation of the various segments of the renogram curve with the intrarenal location and transit of iodohippurate I 131 at that time. Several variations and abnormalities of renogram contour have been characterized in this manner. The results obtained indicate that scintillation-camera renography may be a useful adjunct in the evaluation of renal function under both clinical and experimental conditions.