Haemoglobulin catabolism: the role of ferrihaems in studies of the degradation pathway (Short Communication)

Abstract
The importance of ferrihaem aggregation in studies of haemoglobin catabolism is assessed in the light of recent work. Experimental evidence is put forward suggesting that monomeric ferrihaems are degraded much more readily than dimeric species. This may offer an alternative explanation for the apparent ‘apoprotein catalysis’ recently observed.