Synthesis of the alkaloids (±)-oxomaritidine and (±)-epimaritidine using an orchestrated multi-step sequence of polymer supported reagents

Abstract

The concise synthesis of the alkaloids (±)-oxomaritidine 1 and (±)-epimaritidine 2 in high yield are described, which employs a sequence of five- and six-step reactions respectively, using solely polymer supported reagents in an orchestrated successive manner.