Lysosomal enzyme levels in human amniotic fluid cells in tissue culture:IV. %A N‐acetyl‐β‐D‐glucosaminidase

Abstract

Total and % activity of hexosaminidase were similar for primary cultures and later passages of amniotic fluid cells. The culture variables, through serial passage, within a passage and replicate primary cultures, resulted in some variation in total hexosaminidase, but an insignificant change in % activity of hexosaminidase. They are unlikely to give rise to any problems in the antenatal diagnosis of Sandhoff''s and Tay-Sachs diseases.