The Simultaneous Spectrophotometric Assay of the Active Constituents of Multicomponent Analgesics Using Kalmanfiltering
- 3 January 1984
- journal article
- pharmaceutical analysis
- Published by Taylor & Francis in Analytical Letters
- Vol. 17 (9), 779-792
- https://doi.org/10.1080/00032718408081480
Abstract
UV-spectrophotometry in combination with Kalmanfiltering is used for the assay of analgesics in tablets. Commercial products containing various combinations of acetylsalicylic acid, salicylic acid, caffeine, phenacetine and acetaminophen are analyzed. For comparison, these tablets were also analyzed by HPLC. The accuracy and precision of both methods are comparable. The described spectrophotometric assay with the aid of Kalmanfiltering represents a new, rapid and low-cost alternative to existing analytical procedures for analgesics.Keywords
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