FRIGHT-THYROTOXICOSIS IN THE WILD RABBIT, A MODEL OF THYROTROPHIC ALARM-REACTION
- 1 April 1954
- journal article
- research article
- Published by Bioscientifica in Acta Endocrinologica
- Vol. 15 (4), 355-367
- https://doi.org/10.1530/acta.0.0150355
Abstract
Thyrotoxicosis in wild rabbits is a model of thyrotropic stress-reaction and is elicited by a psychological trauma. This was shown by histopathological changes and by I131-tests. Accordingly, 3 phases were distinguished alarm reaction, stage of resistance and stage of exhaustion. The adrenal cortex of the wild rabbit was unaffected by this special type of stress. The increase of thyrotropic hormone implied an ACTH-stop, which could only be acutely interrupted by additional stressors such as histamine, epinephrine, formalin, ACTH or continued specific or non-specific infections.Keywords
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