PHASE-II CLINICAL-TRIAL OF CIS-DICHLORODIAMMINEPLATINUM IN GASTRIC-CANCER
- 1 January 1983
- journal article
- research article
- Vol. 6 (1), 35-38
Abstract
Eighteen patients with gastric cancer in Stage 4 who had failed combination chemotherapy were treated with cis-dichlorodiammineplatinum as a single agent. Objective response was observed in 4 patients (22%), and another 2 had stable disease lasting 114 and 234 days, respectively. The median duration of the response was 150 days (range, 92-186). Gastrointestinal toxicity occurred in all the patients, but leukopenia and thrombocytopenia was the major complication in patients who had been heavily pretreated. The response rate found in this study shows that cis-platinum is an active drug in gastric cancer.This publication has 9 references indexed in Scilit:
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