Cimetidine—A Non-Thiourea H2-Receptor Antagonist
- 1 March 1975
- journal article
- research article
- Published by SAGE Publications in Journal of International Medical Research
- Vol. 3 (2), 86-92
- https://doi.org/10.1177/030006057500300205
Abstract
Cimetidine is a non-thiourea analogue of metiamide. It is a specific competitive histamine H2-receptor antagonist and is an effective inhibitor of gastric secretion in animals and man with similar pharmacological properties to metiamide. No renal damage or haematological changes were observed in 90-day studies in rats or dogs.Keywords
This publication has 6 references indexed in Scilit:
- Relief of duodenal ulcer sysmptons by oral metiamide.BMJ, 1975
- NEUTROPENIA ASSOCIATED WITH METIAMIDEThe Lancet, 1975
- INHIBITION OF NOCTURNAL ACID SECRETION IN DUODENAL ULCER BY ONE ORAL DOSE OF METIAMIDEThe Lancet, 1974
- Metiamide — An orally active histamine H2-receptor antagonistInflammation Research, 1973
- Definition and Antagonism of Histamine H2-receptorsNature, 1972
- RECEPTORS MEDIATING SOME ACTIONS OF HISTAMINEBritish Journal of Pharmacology and Chemotherapy, 1966